- Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients) ( 2005 ) /10 Protein and Amino Acids National Academic Press
- L-asparagine PubChem
- Alfadhel M et al, 2015, Asparagine Synthetase Deficiency: New Inborn Errors of Metabolism PubMed Central
What is asparagine?
Asparagine is a nonessential amino acid . It can be produced in your body from aspartic acid, so you do not need to get it from foods in order to be healthy . In foods, asparagine is incorporated into proteins.
Asparagine abbreviation (symbol): Asn
Asparagine Functions in the Human Body
Asparagine is :
- A building block of proteins
- A precursor of aspartate
- A glucogenic amino acid — it can be converted into glucose
- A mild diuretic
- Important for removal of nitrogenous wastes
Foods High in Asparagine
- ANIMAL FOODS: meat, fish, cheese
- PLANT FOODS: legumes, seeds, nuts, asparagus
Foods low in asparagine: fruits, vegetables
Nonprescription (over-the-counter) oral L-asparagine supplements are available.
Asparagine Health Benefits
There seems to be NO EVIDENCE about the effectiveness of l-asparagine supplements in the prevention or treatment of Alzheimer’s disease or cancer or in improving kidney or liver function.
Asparagine Safety: Side Effects, Toxicity
Allergic reactions to l-asparagine are possible.
Asparagine Synthetase Deficiency
Asparagine synthetase deficiency is a recently discovered hereditary metabolic disorder in which asparagine cannot be synthesized in sufficient amounts due to lack of the enzyme asparagine synthetase . Symptoms are present at birth and may include small head size (microcephaly) and seizures. Asparagine supplements may help relieve the progress of the disease but not cure it, since abnormalities are present at birth .